Winner takes all in a race for cell fate

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Winner takes all in a race for cell fate

The choice between alternative cell fates is fundamental to biology. The Gram-positive soil bacterium Bacillus subtilis can become competent for genetic transformation by external DNA or can form resistant spores. Although decades of work has elucidated much about the complex regulatory pathways that lead to these mutually exclusive fates (Dubnau and Losick, 2006), the decision mechanism that d...

متن کامل

A Stochastic Competitive R&D Race Where "Winner Takes All"

The paper considers an environment in which multiple firms compete over the development of a product. The first firm to complete the project gains a reward whereas the other firms gain nothing. The decisions of the firms are the level of investment in the project and these decisions affect the random (exponential) completion time. The paper provides a method for explicitly computing a unique Na...

متن کامل

The winner takes it all.

W e all make mistakes from time to time. I have made my fair share, but none of my mistakes have ever won a prize. In 2002 Lundbeck breached the UK industry code of practice in the way it advertised escitalopram (Cipralex). Escitalopram is the son of citalopram (Cipramil). The company claimed that its new drug, escitalopram was more effective than citalopram, even though the two drugs have exac...

متن کامل

The winner takes it all

We study competing first passage percolation on graphs generated by the configuration model. At time 0, vertex 1 and vertex 2 are infected with the type 1 and the type 2 infection, respectively, and an uninfected vertex then becomes type 1 (2) infected at rate λ1 (λ2) times the number of edges connecting it to a type 1 (2) infected neighbor. Our main result is that, if the degree distribution i...

متن کامل

A Stochastic Competitive Research and Development Race Where "Winner Takes All" with Lower and Upper Bounds

The paper analyzes an environment in which several firms compete over the development of a project. Each firm decides how much to invest in the project while adhering to firm-specific lower and upper investment bounds. The completion time of the project by a firm has exponential distribution with rate that depends linearly on the investment of the firm. The firm that completes the project first...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Molecular Systems Biology

سال: 2011

ISSN: 1744-4292,1744-4292

DOI: 10.1038/msb.2011.92